Thioacetamide → HCID 22316705、化合物
反応式
Br[CH:2]([C:13]1[CH:18]=[CH:17][C:16]([Br:19])=[CH:15][CH:14]=1)[C:3]([C:5]1[CH:10]=[CH:9][C:8]([S:11][CH3:12])=[CH:7][CH:6]=1)=O.[C:20]([NH2:23])(=[S:22])[CH3:21]>C(O)C>[Br:19][C:16]1[CH:17]=[CH:18][C:13]([C:2]2[S:22][C:20]([CH3:21])=[N:23][C:3]=2[C:5]2[CH:10]=[CH:9][C:8]([S:11][CH3:12])=[CH:7][CH:6]=2)=[CH:14][CH:15]=1参加物
4
実験手順
A mixture of 2-bromo-2-(4-bromophenyl)-1-(4-methylthiophenyl)ethanone (7.6 g, 0.018 mol) and thioacetamide 1.4 g, 0.018 mol) in ethanol (150 mL) was refluxed for 1 day. The mixture was concentrated and the solid was purified by flash chromatography eluting with CH2Cl2/hexane (2/1) to give title compound (3.8 g, 56%).
後処理
- temperaturewas refluxed for 1 day
- concentrationThe mixture was concentrated
- customthe solid was purified by flash chromatography
- washeluting with CH2Cl2/hexane (2/1)
出典と根拠
- ORDレコード
- ord-1ce19b405f7247c18b8fe4e04c644688
- 出典データセット
- uspto-grants-2004_04
- 特許番号
- US06727238B2
反応ノート
読み込み中…