p-Chlorophenacyl bromide → 5-(4-Chlorophenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one
反応式
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][CH:6]=1)=O.C[O:13][C:14]([NH:16][NH2:17])=[S:15]>C(#N)C>[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2[CH2:2][S:15][C:14](=[O:13])[NH:16][N:17]=2)=[CH:6][CH:7]=1参加物
4
実験手順
A mixture of 2-bromo-p-chloroacetophenone (9.16 g), methoxythiocarbonylhydrazine (13.0 g) and acetonitrile (75 ml) was refluxed overnight and then cooled and filtered. The light yellow solid was washed with hexane and dried yielding 5-(4-chlorophenyl)-3H,6H-1,3,4-thiadiazin-2-one (4.3 g).
後処理
- temperaturewas refluxed overnight
- temperaturecooled
- filtrationfiltered
- washThe light yellow solid was washed with hexane
- customdried
出典と根拠
- ORDレコード
- ord-be3327987e254f7c83d2e21521f5ed8d
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05728694
反応ノート
読み込み中…