4-Formyl-3-vinylbenzonitrile → 3-Ethyl-4-formylbenzonitrile

HRID 2090194ノート

反応式

HRID 2090194 の反応式
[CH:1]([C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[CH:11]=[CH2:12])=[O:2]>C(O)C.[Pd]>[CH2:11]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:3]=1[CH:1]=[O:2])[C:7]#[N:8])[CH3:12]

参加物

4

反応物 1

HCID 540496494-Formyl-3-vinylbenzonitrile

生成物 1

HCID 178193273-Ethyl-4-formylbenzonitrile

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 1.3 g (8.27 mmol) of 4-formyl-3-vinylbenzonitrile in 35 ml of ethanol is mixed with 880 mg of 10% palladium on carbon and vigorously stirred under a hydrogen atmosphere for 2 h. The suspension is filtered through a layer of kieselguhr, the residue is washed with ethanol, and the filtrate is concentrated. The residue (890 mg) is employed without further purification in the following stage.

後処理

  1. filtrationThe suspension is filtered through a layer of kieselguhr
  2. washthe residue is washed with ethanol
  3. concentrationthe filtrate is concentrated
  4. customThe residue (890 mg) is employed without further purification in the following stage

出典と根拠

ORDレコード
ord-20fd7af940644ccda0ad9449634d72c6
出典データセット
uspto-grants-2013_05
特許番号
US08436180B2

反応ノート

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