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Nitric Acid → N-[4-(dimethylamino)-2-nitrophenyl]acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 4'-Dimethylaminoacetanilide | HCID 81968 | — |
| 生成物 | N-[4-(dimethylamino)-2-nitrophenyl]acetamide | HCID 4396139 | — |
反応手順
N-[4-(dimethylamino)phenyl]acetamide obtained in step I above was nitrated using nitric acid (1.2 eq)+H2SO4 (1.0 eq) at 0 to 5° C. for 2 hrs. After the completion of the reaction, reaction mixture was added to ice and pH was adjusted to 8, extracted with dichloromethane, which was evaporated to dryness to obtain N-[4-(dimethylamino)-2-nitrophenyl]acetamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08440830B2 |
| 出典データセット | uspto-grants-2013_05 |
| ORD ID | ord-d2a14774e774469797592a2ed1dfd384 |
| 出典メモ | uspto-grants-2013_05 |