Hydrogen Bromide → HCID 11063219、化合物
反応式
Br.C[O:3][C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[CH2:15][CH2:14][CH2:13][C:12](=[O:16])[CH2:11]2)=[CH:6][CH:5]=1>C(OC(=O)C)(=O)C>[OH:3][C:4]1[CH:5]=[CH:6][C:7]([CH:10]2[CH2:15][CH2:14][CH2:13][C:12](=[O:16])[CH2:11]2)=[CH:8][CH:9]=1参加物
4
実験手順
2.12 ml of 48% aqueous hydrobromic acid are added slowly to 1.28 g of 3-(4-methoxyphenyl)cyclohexanone in 6.4 ml of acetic anhydride. After 4 hours at reflux, the reaction mixture is poured into ice-water and extracted with diethyl ether. After concentration of the organic phase and purification over silica gel, 3-(4-hydroxyphenyl)cyclohexanone is obtained in the form of an oil.
後処理
- temperatureAfter 4 hours at reflux
- extractionextracted with diethyl ether
- customAfter concentration of the organic phase and purification over silica gel
出典と根拠
- ORDレコード
- ord-da0548bd83d0456f861ce3064ddfed15
- 出典データセット
- uspto-grants-2009_08
- 特許番号
- US07569727B2
反応ノート
読み込み中…