Hydrochloric Acid → HCID 76608766、化合物

HRID 2100752ノート

反応式

HRID 2100752 の反応式
[CH3:1][N:2]([CH3:17])[C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[CH2:10][CH2:9][C:8]2=[O:16])=[O:4].C([O:22][N:23]=O)CCC.Cl>CO.O1CCOCC1>[CH3:17][N:2]([CH3:1])[C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[CH2:10][C:9](=[N:23][OH:22])[C:8]2=[O:16])=[O:4]

参加物

6

反応物 3

HCID 313Hydrochloric AcidHCID 10996Butyl nitriteHCID 57799672HCID 57799672、化合物

生成物 1

HCID 76608766HCID 76608766、化合物収率 97.3%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 312751,4-Dioxane溶媒

実験手順

To a solution of 6-Methoxy-3-oxo-indan-5-carboxylic acid dimethylamide (2.56 g, 10.97 mmol) in the methanol (40 ml) and dioxane (40 ml) was added n-butylnitrite (1.48 ml, 12.067 mmol) followed by concentrated HCl (1 ml). The solution was stirred at r.t overnight during which time a precipitate was formed. The precipitate was collected and dried to yield a yellow solid (2.8 g, 97%). LC-MS: m/e 263 (MH+).

後処理

  1. customwas formed
  2. customThe precipitate was collected
  3. customdried

出典と根拠

ORDレコード
ord-813776e1eaa547138b7bbac4185b6194
出典データセット
uspto-grants-2009_08
特許番号
US07572809B2

反応ノート

読み込み中…