Benzoyl Peroxide → HCID 46938920、化合物

反応式

[Br:1]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.[F:27][C:28]([F:44])([F:43])[C:29](=[O:42])[CH2:30][C:31]([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1[O:40][CH3:41])([CH3:33])[CH3:32]>C(Cl)(Cl)(Cl)Cl>[F:27][C:28]([F:43])([F:44])[C:29](=[O:42])[CH2:30][C:31]([C:34]1[CH:39]=[C:38]([Br:1])[CH:37]=[CH:36][C:35]=1[O:40][CH3:41])([CH3:33])[CH3:32]

参加物

実験手順

A mixture of N-bromosuccinimide (6.84 g, 38.42 mmol), benzoylperoxide (catalytic amount) and 1,1,1-trifluoro-4-(2-methoxyphenyl)-4-methylpentan-2-one (10.0 g, 38.42 mmol) in carbon tetrachloride (120 mL) and was refluxed for two days. After cooling, the solution was washed with water (60 mL) and 1.0M NaOH (60 mL), dried over sodium sulfate (Na2SO4), and concentrated in vacuo giving 1,1,1-trifluoro-4-(5-bromo-2-methoxyphenyl)-4-methylpentan-2-one and the starting material as 3:1 mixture (13.0 g).