Acetic Anhydride → Ethyl 2-acetoxy-5-benzylideneaminobenzoate

HRID 2107015ノート

反応式

HRID 2107015 の反応式
[OH:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].[C:21](OC(=O)C)(=[O:23])[CH3:22]>N1C=CC=CC=1>[C:21]([O:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5])(=[O:23])[CH3:22]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 23047228Ethyl 2-hydroxy-5-benzylideneaminobenzoate

生成物 1

HCID 23047223Ethyl 2-acetoxy-5-benzylideneaminobenzoate収率 73%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Ethyl 2-hydroxy-5-benzylideneaminobenzoate (21 g, 78 mmole) was dissolved in pyridine (60 ml) and acetic anhydride (8.9 ml) was added after which the reaction mixture was kept at room temperature for 48 hours, evaporated to dryness in vacuo, and the residue recrystallized from hexane to give the title compound (17.8 g, 73%), m.p. 79°-80° C. Found (Calc. for C18H17NO4) C 69.33 (69.45), H 5.51 (5.47), N 4.57 (4.50).

後処理

  1. customevaporated to dryness in vacuo
  2. customthe residue recrystallized from hexane

出典と根拠

ORDレコード
ord-e0729028dcb146fbaadc5cd8b27ca884
出典データセット
uspto-grants-1990_06
特許番号
US04933330

反応ノート

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