Hydroxyamine hydrochloride → HCID 136364614、化合物
反応式
[CH2:1]([O:8][C:9]1[CH:21]=[CH:20][CH:19]=[C:18]2[C:10]=1[C:11]1[C:12]([CH2:34][O:35][CH3:36])=[C:13]([CH:32]=O)[N:14]=[CH:15][C:16]=1[N:17]2[S:22]([C:25]1[CH:31]=[CH:30][C:28]([CH3:29])=[CH:27][CH:26]=1)(=[O:24])=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:38][OH:39]>C(O)C>[CH2:1]([O:8][C:9]1[CH:21]=[CH:20][CH:19]=[C:18]2[C:10]=1[C:11]1[C:12]([CH2:34][O:35][CH3:36])=[C:13]([CH:32]=[N:38][OH:39])[N:14]=[CH:15][C:16]=1[N:17]2[S:22]([C:25]1[CH:31]=[CH:30][C:28]([CH3:29])=[CH:27][CH:26]=1)(=[O:23])=[O:24])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
500 mg of 5-benzyloxy-4-methoxymethyl-9-tosyl-β-carboline-3-carbaldehyde is heated in 15 ml of ethanol to 70° C., combined with 84 mg of hydroxylamine hydrochloride in 10 ml of ethanol and heated for 1.5 hours to 70° C. Then the mixture is concentrated to 5 ml, poured on 40 ml of water, and suctioned off. The residue (450 mg) is utilized after drying in the subsequent stage without further purification.