Ethyl 2-[(2-methylphenyl)amino]-4-thiazolecarboxylate → HCID 16769476、化合物

HRID 2107263ノート

反応式

HRID 2107263 の反応式
[C:1]1([CH3:18])[C:2]([NH:7][C:8]2[S:9][CH:10]=[C:11]([C:13](OCC)=[O:14])[N:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[C:1]1([CH3:18])[C:2]([NH:7][C:8]2[S:9][CH:10]=[C:11]([CH2:13][OH:14])[N:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 2

HCID 1284666Ethyl 2-[(2-methylphenyl)amino]-4-thiazolecarboxylateHCID 21226445Aluminium lithium hydride

生成物 1

HCID 16769476HCID 16769476、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Following a procedure similar to that described in Preparation 15, the desired compound was prepared from 10 g of ethyl 2-o-toluidinothiazole-4-carboxylate, 2.9 g of lithium aluminum hydride and 200 ml of tetrahydrofuran. The resulting product was a brown oil having the following physical properties.

後処理

  1. customthat described in Preparation 15

出典と根拠

ORDレコード
ord-c9f0ede297a740998ad68a5a2cd9e231
出典データセット
uspto-grants-1990_06
特許番号
US04933355

反応ノート

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