Pyrrolidine → HCID 23045568、化合物
反応式
CC(C)[CH2:3][O:4]CC1OC1.N1CCCC1.C[CH:16]([CH3:28])[CH2:17][O:18][CH2:19][CH:20]([OH:27])[CH2:21][N:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1>C(O)C>[CH3:3][O:4][CH:16]([CH3:28])[CH2:17][O:18][CH2:19][CH:20]([OH:27])[CH2:21][N:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1参加物
5
実験手順
20 g. 1-(2-Methylpropoxy)-2,3-epoxypropane are dissolved in 40 ml. ethanol and the solution is warmed to 55° C. Subsequently, in the course of an hour and while stirring, there is added dropwise a solution of 13 g. pyrrolidine in 25 ml. ethanol. The temperature should thereby not increase above 70° C. After completion of the addition, stirring is continued for 1 hour at 70° C., the reaction mixture is then evaporated and the residue is distilled in a vacuum. There are obtained 35 g. 3-(2-methylpropoxy)-1-pyrrolidinopropan-2-ol; b.p. 134° C./14 mm.Hg.