1-Chloro-2-(diethylamine)ethane hydrochloride → HCID 69065330、化合物

HRID 2109022ノート

反応式

HRID 2109022 の反応式
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([OH:13])=[O:12])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[OH-].[Na+].[CH3:16][CH2:17][N:18]([CH2:21][CH2:22]Cl)[CH2:19][CH3:20].Cl>O>[C:1]([NH:4][C:5]1[CH:6]=[CH:7][C:8]([S:11]([CH2:16][CH2:17][N:18]([CH2:21][CH3:22])[CH2:19][CH3:20])(=[O:13])=[O:12])=[CH:9][CH:10]=1)(=[O:3])[CH3:2]

参加物

5

反応物 3

HCID 133631-Chloro-2-(diethylamine)ethane hydrochlorideHCID 14798Sodium Hydroxide2 回HCID 4121504-(Acetylamino)benzenesulfinic acid

生成物 1

HCID 69065330HCID 69065330、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

9.0 g of 4-acetamido-phenylsulphinic acid are dissolved in 10 ml of water and 45 ml of 1N sodium hydroxide solution and 9.47 g of 2-chlorotriethylamine hydrochloride are added. The mixture is stirred for 5 hours at reflux temperature. After cooling, sodium hydroxide solution is added until an alkaline reaction is obtained, the mixture is extracted with ethyl acetate, dried over magnesium sulphate and finally the solvent is eliminated.

後処理

  1. temperatureat reflux temperature
  2. temperatureAfter cooling
  3. customis obtained
  4. extractionthe mixture is extracted with ethyl acetate
  5. dry with materialdried over magnesium sulphate

出典と根拠

ORDレコード
ord-d6396b351f864c0abea1e4bff9a0de9c
出典データセット
uspto-grants-2009_04
特許番号
US07514468B2

反応ノート

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