Hydrochloric Acid → HCID 68851533、化合物
反応式
[O:1]=[C:2]1[NH:6][CH2:5][CH2:4][N:3]1[C:7]1[CH:8]=[C:9]([CH:12]=[CH:13][CH:14]=1)[C:10]#[N:11].[ClH:15]>CO.[Pd]>[ClH:15].[NH2:11][CH2:10][C:9]1[CH:8]=[C:7]([N:3]2[CH2:4][CH2:5][NH:6][C:2]2=[O:1])[CH:14]=[CH:13][CH:12]=1参加物
5
実験手順
40.00 g (210 mmol) 3-(2-oxo-imidazolidin-1-yl)-benzonitrile are suspended in 1500 ml of methanol, 53 ml of 37% hydrochloric acid are added. The mixture is hydrogenated for 20 hours at ambient temperature under a pressure of 7 bar with 4.00 g palladium/charcoal. The catalyst is filtered off, the filtrate is concentrated and the precipitate formed is suction filtered, washed with acetone and dried.
後処理
- filtrationThe catalyst is filtered off
- concentrationthe filtrate is concentrated
- customthe precipitate formed
- filtrationfiltered
- washwashed with acetone
- customdried
出典と根拠
- ORDレコード
- ord-59e6400b443444628510449f87ad9823
- 出典データセット
- uspto-grants-2009_04
- 特許番号
- US07517995B2
反応ノート
読み込み中…