Trifluoroacetic acid → HCID 68827546、化合物
反応式
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[N:22]=[CH:21][N:20]=[C:19]3[C:15]=2[N:16]([CH2:24][C:25]#[C:26][CH3:27])[C:17](=[O:23])[NH:18]3)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31]>>[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31].[CH2:24]([N:16]1[C:15]2[C:19](=[N:20][CH:21]=[N:22][C:14]=2[N:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)[NH:18][C:17]1=[O:23])[C:25]#[C:26][CH3:27]参加物
3
実験手順
4-[7-(2-Butynyl)-8-oxo-8,9-dihydro-7H-purin-6-yl]piperazine-1-carboxylic acid t-butyl ester (compound 61e) (12 mg) was dissolved in trifluoroacetic acid. This reaction solution was stirred at room temperature for five minutes, and then concentrated. The residue was purified by reverse phase high performance liquid chromatography to give the title compound (8.86 mg).
後処理
- concentrationconcentrated
- customThe residue was purified by reverse phase high performance liquid chromatography
出典と根拠
- ORDレコード
- ord-cce7e992ac5047089da1151eaf1583c8