Oxaloacetic Acid → 4-Hydroxy-4-(3-indolylmethyl)-2-ketoglutaric acid
反応式
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1CC(=O)C(O)=O.[C:16]([OH:21])(=[O:20])[C:17]([CH3:19])=[O:18].C(O)(=O)[CH2:23][C:24]([C:26]([OH:28])=[O:27])=[O:25]>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:23][C:24]([OH:25])([C:26]([OH:28])=[O:27])[CH2:19][C:17](=[O:18])[C:16]([OH:21])=[O:20])=[CH:2]1参加物
4
実験手順
According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).
出典と根拠
- ORDレコード
- ord-7a3e402a4a8b4604936da49f3e7c46ea
- 出典データセット
- uspto-grants-2008_10
- DOI