Ethanolamine → 4-(2-Hydroxy-ethylamino)-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide

反応式

[F:1][c:2]1[c:3]([C:31]([F:32])([F:33])[F:34])[cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][C:10]([NH:11][CH:12]2[CH2:13][N:14]([CH:16]3[CH2:17][CH2:18][CH:19]([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:20][CH2:21]3)[CH2:15]2)=[O:28])[cH:29][cH:30]1.[NH2:35][CH2:36][CH2:37][OH:38]>>[c:2]1([NH:35][CH2:36][CH2:37][OH:38])[c:3]([C:31]([F:32])([F:33])[F:34])[cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][C:10]([NH:11][CH:12]2[CH2:13][N:14]([CH:16]3[CH2:17][CH2:18][CH:19]([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:20][CH2:21]3)[CH2:15]2)=[O:28])[cH:29][cH:30]1

参加物

反応物 2

HCID 700Ethanolamine

HCID 497632274-Fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide

生成物 1

HCID 497633394-(2-Hydroxy-ethylamino)-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide

出典と根拠

ORDレコード: ord-eadaec93dbfd4026b6922654ed395126
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…