Tetrahydrofuran → (2RS,4SR)-4-(3-benzyloxyphenyl)-4-hydroxy-2-methyltetrahydropyran

反応式

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Br:15])[cH:12][cH:13][cH:14]1.[CH3:17][CH:18]1[O:19][CH2:20][CH2:21][C:22](=[O:24])[CH2:23]1.[Mg:16].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([C:22]2([OH:24])[CH2:21][CH2:20][O:19][CH:18]([CH3:17])[CH2:23]2)[cH:12][cH:13][cH:14]1