Hydrofluoric Acid → 1-(2-Chloro-5-fluoropyrimidin-4-yl)ethanone

HRID 212627ノート

反応式

HRID 212627 の反応式
[Br:1][CH2:2][C:3]([c:4]1[cH:5][cH:6][n:7][c:8]([Cl:9])[cH:10]1)=[O:11].[Br:31][CH2:32][C:33]([c:34]1[cH:35][cH:36][n:37][c:38]([S:39][CH3:40])[n:41]1)=[O:42].[Br:44][CH2:45][C:46](=[O:47])[c:48]1[n:49][c:50]([Cl:55])[n:51][cH:52][c:53]1[F:54].[Cl:12][c:13]1[cH:14][c:15]([C:16](=[O:17])[CH3:18])[cH:19][cH:20][n:21]1.[Cl:22][c:23]1[cH:24][c:25]([C:26]#[N:27])[cH:28][cH:29][n:30]1.[F:43]>>[CH3:45][C:46](=[O:47])[c:48]1[n:49][c:50]([Cl:55])[n:51][cH:52][c:53]1[F:54]

参加物

7

反応物 6

HCID 14917Hydrofluoric AcidHCID 5686382-Chloro-4-cyanopyridineHCID 131452551-(2-Chloropyridin-4-yl)ethan-1-oneHCID 167204312-Bromo-1-(2-chloropyridin-4-yl)ethanoneHCID 426090692-Bromo-1-(2-(methylthio)pyrimidin-4-yl)ethanoneHCID 865947392-Bromo-1-(2-chloro-5-fluoropyrimidin-4-yl)ethanone

生成物 1

HCID 865947381-(2-Chloro-5-fluoropyrimidin-4-yl)ethanone

出典と根拠

ORDレコード
ord-ba4b00afe4254f9c8f4b0a441438005d
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反応ノート

読み込み中…