Methanol → N-[3,5-bis(trifluoromethyl)phenyl]-4-(2-{[(2,3,5,6-tetrafluoropyridin-4-yl)amino]methyl}phenyl)piperazine-1-carboxamide

反応式

[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:50][C:51]#[N:52].[CH3:53][OH:54].[F:1][C:2]([c:3]1[cH:4][c:5]([NH:13][C:14](=[O:15])[N:16]2[CH2:17][CH2:18][N:19]([c:22]3[c:23]([CH2:28][NH2:29])[cH:24][cH:25][cH:26][cH:27]3)[CH2:20][CH2:21]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:30])[F:31].[F:39][c:40]1[c:41]([F:49])[c:42]([F:48])[c:43]([F:47])[c:44]([F:46])[n:45]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([NH:13][C:14](=[O:15])[N:16]2[CH2:17][CH2:18][N:19]([c:22]3[c:23]([CH2:28][NH:29][c:42]4[c:41]([F:49])[c:40]([F:39])[n:45][c:44]([F:46])[c:43]4[F:47])[cH:24][cH:25][cH:26][cH:27]3)[CH2:20][CH2:21]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:30])[F:31]