Potassium Cation → [3-(3,5-Difluoro-pyridin-2-yl)-4-methyl-phenyl]-[2-(1,1-dioxo-tetrahydro-thiophen-3-yl)-1,2,3,4-tetrahydro-isoquinolin-5-yl]-amine

HRID 2147015

反応式

[Br:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH2:7][N:6]([CH:12]1[CH2:13][S:14](=[O:17])(=[O:18])[CH2:15][CH2:16]1)[CH2:5][CH2:4]2.[F:19][c:20]1[c:21](-[c:27]2[cH:28][c:29]([NH2:30])[cH:31][cH:32][c:33]2[CH3:34])[n:22][cH:23][c:24]([F:26])[cH:25]1.[K+:40].[K+:41].[K+:42].[O:45]=[C:46]([CH:47]=[CH:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1)[CH:55]=[CH:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[O:63]=[C:64]([CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1)[CH:73]=[CH:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[O:81]=[C:82]([CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1)[CH:91]=[CH:92][c:93]1[cH:94][cH:95][cH:96][cH:97][cH:98]1.[O:99]1[CH2:100][CH2:101][O:102][CH2:103][CH2:104]1.[P:35]([O-:36])([O-:37])([O-:38])=[O:39].[Pd:43].[Pd:44]>>[c:2]1([NH:30][c:29]2[cH:28][c:27](-[c:21]3[c:20]([F:19])[cH:25][c:24]([F:26])[cH:23][n:22]3)[c:33]([CH3:34])[cH:32][cH:31]2)[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH2:7][N:6]([CH:12]1[CH2:13][S:14](=[O:17])(=[O:18])[CH2:15][CH2:16]1)[CH2:5][CH2:4]2