Tetrahydrofuran → 2-Chloro-5-fluoro-N-(3-{3-[2-(3-fluoro-phenylamino)-pyrimidin-4-yl]-pyrazolo[1,5-a]pyridin-2-yl}-phenyl)-benzamide

HRID 2147420

反応式

HRID 2147420 の反応式
[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[Cl:31][c:32]1[c:33]([C:34](=[O:35])[Cl:36])[cH:37][c:38]([F:41])[cH:39][cH:40]1.[NH2:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][c:26]([F:30])[cH:27][cH:28][cH:29]3)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][c:26]([F:30])[cH:27][cH:28][cH:29]3)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1)[C:34]([c:33]1[c:32]([Cl:31])[cH:40][cH:39][c:38]([F:41])[cH:37]1)=[O:35]

参加物

5

反応物 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 27575402-Chloro-5-fluorobenzoyl chlorideHCID 595114034-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-fluorophenyl)-2-pyrimidinamine

生成物 1

HCID 595137492-Chloro-5-fluoro-N-(3-{3-[2-(3-fluoro-phenylamino)-pyrimidin-4-yl]-pyrazolo[1,5-a]pyridin-2-yl}-phenyl)-benzamide

出典と根拠

ORDレコード
ord-618b7950eae04506bd6e27ddba0506ad
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

関連ノート

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