Tetrahydrofuran → 2-(cyanomethylamino)-6-oxo-4-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-1H-pyrimidine-5-carbonitrile

反応式

[BH4-:28].[CH2:1]([CH:2]=[CH2:3])[n:4]1[c:5]([NH:24][CH2:25][C:26]#[N:27])[n:6][c:7]([N:13]2[CH2:14][CH2:15][c:16]3[c:17]([cH:20][cH:21][cH:22][cH:23]3)[CH2:18][CH2:19]2)[c:8]([C:11]#[N:12])[c:9]1=[O:10].[Li+:29].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[nH:4]1[c:5]([NH:24][CH2:25][C:26]#[N:27])[n:6][c:7]([N:13]2[CH2:14][CH2:15][c:16]3[c:17]([cH:20][cH:21][cH:22][cH:23]3)[CH2:18][CH2:19]2)[c:8]([C:11]#[N:12])[c:9]1=[O:10]