Dichloromethane → 3-Phenylcarbamoyl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester

反応式

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]2[N:12]([C:25](=[O:26])[O:27][CH2:28][c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[CH2:13][CH:14]([C:16]([NH:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:24])[CH:15]12)([CH3:5])([CH3:6])[CH3:7].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[NH:8]1[CH2:9][CH2:10][CH:11]2[N:12]([C:25](=[O:26])[O:27][CH2:28][c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[CH2:13][CH:14]([C:16]([NH:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:24])[CH:15]12

参加物

反応物 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 672812753-Phenylcarbamoyl-hexahydro-pyrrolo[3,2-b]pyrrole-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester

生成物 1

HCID 672812863-Phenylcarbamoyl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester

出典と根拠

ORDレコード: ord-6d7d529066554229b2ab8778ab66c6d0
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…