化工社化工社 化学情報印刷レポート · 研究参考用
(R)-(+)-1-Boc-3-aminopyrrolidine → (R)-3-Amino-pyrrolidine-1-carboxylic acid (R)-pyrrolidin-3-ylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-(+)-1-Boc-3-aminopyrrolidine | HCID 854070 | — |
| 反応物 | (R)-3-Amino-pyrrolidine-1-carboxylic acid (4-amino-cyclohexyl)-amide | HCID 67022910 | — |
| 生成物 | (R)-3-Amino-pyrrolidine-1-carboxylic acid (R)-pyrrolidin-3-ylamide | HCID 58025012 | — |
反応手順
(R)-3-Amino-pyrrolidine-1-carboxylic acid (R)-pyrrolidin-3-ylamide is prepared analogously to (R)-3-amino-pyrrolidine-1-carboxylic acid (4-amino-cyclohexyl)-amide (Intermediate IF) by replacing (4-amino-cyclohexyl)-carbamic acid tert-butyl ester with (R)-3-amino-pyrrolidine-1-carboxylic acid tert-butyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08193164B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-983da489732248f1890945b0fd8bd093 |
| 出典メモ | uspto-grants-2012_06 |