Diethyl Ether → HCID 23462418、化合物
反応式
[CH3:1][C:2]1[N:3]2[CH:9]=[C:8]([CH2:10]O)[N:7]=[C:4]2[S:5][CH:6]=1.CCOCC.O=S(Cl)[Cl:19]>>[ClH:19].[CH3:1][C:2]1[N:3]2[CH:9]=[C:8]([CH2:10][Cl:19])[N:7]=[C:4]2[S:5][CH:6]=1参加物
4
実験手順
10 g of 3-methyl-6-hydroxymethyl-imidazo-(2,1-b)thiazole prepared as described in one of the methods in Example 26, is refluxed for 2 hours in 100 ml of SOCl2. The solution is then cooled, 50 ml of ether are added to yield 11 g of 3-methyl-6-chloromethyl-imidazo-(2,1-b)thiazole hydrochloride; m.p. 280°.
後処理
- temperatureThe solution is then cooled
出典と根拠
- ORDレコード
- ord-4f2b1bb0ce124878a54aeb9667cba231
- 出典データセット
- uspto-grants-1979_01
- 特許番号
- US04137320
反応ノート
読み込み中…