Hydrochloric Acid → HCID 14452901、化合物

HRID 2165260ノート

反応式

HRID 2165260 の反応式
[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[C:6]([Cl:11])[CH:5]=[C:4]([CH2:12][CH3:13])[N:3]=1.Cl[Sn]Cl.Cl.[OH-].[Na+]>>[NH2:8][C:7]1[C:2]([Cl:1])=[N:3][C:4]([CH2:12][CH3:13])=[CH:5][C:6]=1[Cl:11]

参加物

5

反応物 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 24479Stannous ChlorideHCID 14452905HCID 14452905、化合物

生成物 1

HCID 14452901HCID 14452901、化合物

実験手順

9 g (40.7 mmol) of 2,4-dichloro-6-ethyl-3-nitropyridine are introduced into a solution of 33 g (0.146 mol) of SnCl2. 2H2O in 100 ml of 36% strength HCl and the mixture is boiled under reflux for 30 minutes. It is then cooled and stirred into 400 ml of 12% strength NaOH with cooling. It is extracted three times using 150 ml of dichloromethane each time and the extract is dried using Na2SO4 and evaporated.

後処理

  1. temperatureunder reflux for 30 minutes
  2. temperatureIt is then cooled
  3. temperaturewith cooling
  4. extractionIt is extracted three times
  5. customthe extract is dried
  6. customevaporated

出典と根拠

ORDレコード
ord-63f2e89df7d746b9bab1be7990dff5b7
出典データセット
uspto-grants-1990_07
特許番号
US04939262

反応ノート

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