Tetrahydrofuran → N'-(3-Bromophenyl)-N,N-dibutylurea
反応式
[Br:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:11])[O-])[CH:5]=[CH:6][CH:7]=1.O1CCCC1.[CH2:17]([NH:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:18][CH2:19][CH3:20]>CCCCCC>[CH2:17]([N:21]([CH2:22][CH2:23][CH2:24][CH3:25])[C:9]([NH:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[CH:3]=1)=[O:11])[CH2:18][CH2:19][CH3:20]参加物
5
実験手順
A solution of 1.46 g. of phenyl N-(3-bromophenylcarbamate in 15 ml. of tetrahydrofuran is added to a solution of 1.52 g. of di-n-butylamine in 20 ml. of tetrahydrofuran and the mixture is stirred under reflux for 24 hours. The mixture is diluted with hexane and the precipitate collected by filtration. Recrystallization from pentane affords 1,1-di-(n-butyl)-3-(3-bromophenyl)urea, m.p. 80°-81° C.
後処理
- temperatureunder reflux for 24 hours
- filtrationthe precipitate collected by filtration
- customRecrystallization from pentane
出典と根拠
- ORDレコード
- ord-f73b2f0f28c641d4ba2658f41d63b3d7
- 出典データセット
- uspto-grants-1983_06
- 特許番号
- US04387105
反応ノート
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