Bromine → HCID 13048358、化合物

HRID 2167690ノート

反応式

HRID 2167690 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:14])[CH2:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][CH:3]=1.[Br:15]Br>C(Cl)(Cl)Cl>[Br:15][CH:9]([C:8]([C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=1)=[O:14])[C:10]([O:12][CH3:13])=[O:11]

参加物

4

反応物 2

HCID 24408Bromine2 回HCID 291780Methyl 3-(4-methylphenyl)-3-oxopropanoate

生成物 1

HCID 13048358HCID 13048358、化合物

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

反応条件

温度
70 °C

実験手順

To a chloroform (20 mL) solution of methyl 3-(4-methylphenyl)-3-oxopropanoate (1.0 g), bromine (0.12 mL) was added, and the resultant was stirred at 70° C. for 1 hour under sealed conditions. Then, bromine (0.12 mL) was further added thereto, and the resultant was further stirred at 70° C. for 1 hour under sealed conditions. The reaction solution was concentrated under reduced pressure to obtain the title compound (1.3 g) as a brown oil.

後処理

  1. stirringthe resultant was further stirred at 70° C. for 1 hour under sealed conditions
  2. concentrationThe reaction solution was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-88afbefa38464bcc93c2d89285a51545
出典データセット
uspto-grants-2015_06
特許番号
US09045466B2

反応ノート

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