1-(p-Chlorophenyl)cyclopentanemethanol → Methanesulfonic acid 1-(4-chlorophenyl)-cyclopentylmethyl ester

HRID 2169154

反応式

HRID 2169154 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([CH2:13][OH:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.C1(C2(C[O:27][S:28]([CH3:31])(=O)=[O:29])CCCC2)C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([CH2:13][O:14][S:28]([CH3:31])(=[O:29])=[O:27])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:6][CH:7]=1

参加物

3

反応物 2

HCID 27240171-(p-Chlorophenyl)cyclopentanemethanolHCID 19437914(1-Phenylcyclopentyl)methyl methanesulfonate

生成物 1

HCID 86725805Methanesulfonic acid 1-(4-chlorophenyl)-cyclopentylmethyl ester収率 93.08%

実験手順

Methanesulfonic acid 1-(4-chlorophenyl)-cyclopentylmethyl ester (24-02) (32 g, 93.08%) was synthesized from [1-(4-chlorophenyl)-cyclopentyl]-methanol (23-02) (25 g, 119.04 mmol) as a crude product as a yellow liquid following the procedure as described for methanesulfonic acid 1-phenyl-cyclopentylmethyl ester (24-01).

出典と根拠

ORDレコード
ord-16ed389b6b5945cd914b15602d2a9074
出典データセット
uspto-grants-2015_06
特許番号
US09045486B2

関連ノート

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