Ibuprofen, (+-)- → HCID 15948295、化合物

HRID 2170008ノート

反応式

HRID 2170008 の反応式
[OH:1][C:2]([CH:4]([C:6]1[CH:15]=[CH:14][C:9]([CH2:10][CH:11]([CH3:13])[CH3:12])=[CH:8][CH:7]=1)[CH3:5])=[O:3].[OH-].[Na+].O.O.O.O.O.O.[Cl-].[Sr+2:25].[Cl-]>O>[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1].[Sr+2:25].[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1]

参加物

5

反応物 3

HCID 3672Ibuprofen, (+-)-HCID 14798Sodium HydroxideHCID 6101868Strontium chloride hexahydrate

生成物 1

HCID 15948295HCID 15948295、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

Ibuprofen (2.59 g, 12.5 mmol) was dissolved in water (100 ml) containing sodium hydroxide (0.503 g, 12.5 mmol). A solution of strontium chloride hexahydrate (1.68 g, 6.3 mmol) in water (5 ml) was added. The mixture was stirred for 10 minutes at room temperature and the title compound was isolated by filtration and dried. Yield 1.30 g (44%). Melting point>300.degree. C.

出典と根拠

ORDレコード
ord-27849d9ff56a4ceb92c3ad2c871b5646
出典データセット
uspto-grants-2015_06
特許番号
US09050312B2

反応ノート

読み込み中…