Tert-butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate → (1-Oxo-1,3-dihydro-2-benzofuran-5-yl)acetic acid
反応式
[O:1]=[C:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][C:12]([O:14]C(C)(C)C)=[O:13])=[CH:10][C:5]=2[CH2:4][O:3]1>C(O)(C(F)(F)F)=O>[O:1]=[C:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][C:12]([OH:14])=[O:13])=[CH:10][C:5]=2[CH2:4][O:3]1参加物
3
実験手順
tert-Butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate (1.2 g, 4.8 mmol) was dissolved in TFA and stirred at room temperature for one h. The reaction mixture was concentrated and pumped under vacuum overnight to afford the title compound. LC-MS (IE, m/z): 193.2 [M+1]+.
後処理
- concentrationThe reaction mixture was concentrated
- custompumped under vacuum overnight
出典と根拠
- ORDレコード
- ord-c62a8fe2907d4f8b86e5442bd5f96207
- 出典データセット
- uspto-grants-2015_06
- 特許番号
- US09056859B2
反応ノート
読み込み中…