Ammonium Chloride → 1-(3,5-Dimethoxyphenyl)ethanol
反応式
[CH3:1][C:2]([C:4]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[C:6]([O:12][CH3:13])[CH:5]=1)=[O:3].[BH4-].[Na+].[Cl-].[NH4+]>CO>[CH3:13][O:12][C:6]1[CH:5]=[C:4]([CH:2]([OH:3])[CH3:1])[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=1参加物
5
実験手順
To a solution of 3,5-dimethoxyacetophenone (1 g; 5.5 mmol) in methanol (30 mL) is added sodium borohydride (315 mg; 8.3 mmol) in four portions over one hour. The reaction is stirred at room temperature overnight, neutralized with saturated ammonium chloride, and extracted with ethyl acetate. The organics are separated, washed with water, and dried over magnesium sulfate. The solvent is removed to give 1.12 grams of 1-(3,5-dimethoxyphenyl)-ethanol.
後処理
- extractionextracted with ethyl acetate
- customThe organics are separated
- washwashed with water
- dry with materialdried over magnesium sulfate
- customThe solvent is removed
出典と根拠
- ORDレコード
- ord-e9be1ecc317c46818765fbf7792412c7
- 出典データセット
- uspto-grants-2015_06
- 特許番号
- US09067897B2
反応ノート
読み込み中…