3-nitro-9-isopropyl-9H-carbazole → HCID 11790847、化合物

HRID 2184931ノート

反応式

HRID 2184931 の反応式
[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([N+:17]([O-])=O)=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]>CCO.[Pd]>[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([NH2:17])=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]

参加物

4

反応物 1

HCID 6174713-nitro-9-isopropyl-9H-carbazole

生成物 1

HCID 11790847HCID 11790847、化合物収率 98.4%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a solution of 9-Isopropyl-3-nitro-9H-carbazole(1.5 g, 5.89 mmol) in EtOH (100 ml) was added 10% Pd-C (150 mg) and the reaction mixture was hydrogenated with a Parr hydrogenation apparatus at 45 psi H2 pressure for 3 hours. The reaction mixture was filtered and the filtrate concentrated in vacuo to afford the desired product as a solid (1.3 g, 87%).

後処理

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate concentrated in vacuo

出典と根拠

ORDレコード
ord-c589a92b2ef6434d939ce04e5de9da8e
出典データセット
uspto-grants-2002_06
特許番号
US06399631B1

反応ノート

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