反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1I)[NH2:5].[CH2:10]([CH:13]1[CH2:18][CH2:17][CH2:16][NH:15][C:14]1=[O:19])[CH:11]=[CH2:12]>>[CH2:10]([CH:13]1[CH2:18][CH2:17][CH2:16][N:15]([C:8]2[CH:7]=[CH:6][C:4]([NH2:5])=[CH:3][C:2]=2[Cl:1])[C:14]1=[O:19])[CH:11]=[CH2:12]参加物
3
実験手順
Analogously to the process described under example 93A, 6.00 g (23.7 mmol) of 3-chloro-4-iodoaniline and 4.11 g (29.6 mmol) of the compound from example 96A are used to obtain 1.57 g (25% of theory) of the title compound. The purification is effected by suction filtration using silica gel with 2:1→1:2 cyclohexane/ethyl acetate as the eluent.
出典と根拠
- ORDレコード
- ord-1072e6521e71422e8b7d16ab4d45c732
- 出典データセット
- uspto-grants-2012_06
- 特許番号
- US08198267B2
関連ノート
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