(Z)-3-(2,3-dimethoxyphenyl)prop-2-enoic acid → 3-(2,3-Dimethoxyphenyl)propanoic acid

HRID 2185635

反応式

HRID 2185635 の反応式
[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1/[CH:11]=[CH:12]\[C:13]([OH:15])=[O:14].[H][H]>CO.[Pd]>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:11][CH2:12][C:13]([OH:15])=[O:14]

参加物

5

反応物 2

HCID 1559386(Z)-3-(2,3-dimethoxyphenyl)prop-2-enoic acidHCID 178418361HCID 178418361、化合物

生成物 1

HCID 3149293-(2,3-Dimethoxyphenyl)propanoic acid収率 95.9%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

Nitrogen was passed through a stirred suspension of (Z)-3-(2,3-dimethoxyphenyl)-2-propenoic acid (14,67 g) in 400 ml of methanol during 15 minutes. Then 1.4 g of 10% palladium on activated carbon were added and a stream of hydrogen was passed through the reaction mixture for 16 hours. After removing the palladium catalyst by filtration, the filtrate was evaporated to yield 14.2 g of 3-(2,3-dimethoxyphenyl)-propanoic acid, M.S. (C.I.) (MZ): 211 [M+H]+.

後処理

  1. customAfter removing the palladium catalyst
  2. filtrationby filtration
  3. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-a470341975dc4476a9234e11b0d07e3d
出典データセット
uspto-grants-2002_06
特許番号
US06403573B1

関連ノート

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