HCID 14691534、化合物 → HCID 23313846、化合物
反応式
[CH3:1][C:2]1([CH3:16])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[C:3]1[C:11]([O:13][CH2:14][CH3:15])=[O:12]>C(O)C.[Pd]>[CH3:1][C:2]1([CH3:16])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[NH:4][CH:3]1[C:11]([O:13][CH2:14][CH3:15])=[O:12]参加物
4
実験手順
Ethyl 3,3-dimethyl-3H-indole-2-carboxylate (4.00 g, 18.4 mmol) was dissolved in ethanol (20 ml) and activated palladium-on-charcoal (0.5 g) was then added to this solution. This mixture was hydrogenated for five hours. After filtration in order to remove the catalyst, the filtrate was dried (MgSO4) and the solvent removed in order to give a brown oil.
後処理
- filtrationAfter filtration in order
- customto remove the catalyst
- dry with materialthe filtrate was dried (MgSO4)
- customthe solvent removed in order
- customto give a brown oil
出典と根拠
- ORDレコード
- ord-aa28a24f8b2e4f17b2040e653840eb2d
- 出典データセット
- uspto-grants-2002_06
- 特許番号
- US06403561B1
反応ノート
読み込み中…