methyl 5-methyl-2,3-dihydro-1H-indole-2-carboxylate → HCID 85707549、化合物
反応式
[CH3:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]([C:11]([O:13]C)=O)[CH2:5]2>C(N)CCC>[CH2:6]([NH:7][C:11]([CH:6]1[CH2:5][C:4]2[C:8](=[CH:9][CH:10]=[C:2]([CH3:1])[CH:3]=2)[NH:7]1)=[O:13])[CH2:5][CH2:4][CH3:3]参加物
3
実験手順
Methyl 5-methylindoline-2(R/S)-carboxylate (0.3 g, 4.18 mmol) was dissolved in butylamine (20 ml) and the mixture was refluxed for 4 h under nitrogen. The excess amine was removed under vacuum to give a solid, which was recrystallized from ether in order to allow the product to be collected.
後処理
- temperaturethe mixture was refluxed for 4 h under nitrogen
- customThe excess amine was removed under vacuum
- customto give a solid, which
- customwas recrystallized from ether in order
- customto be collected
出典と根拠
- ORDレコード
- ord-239c0ba8916541089e8bd93385a52246
- 出典データセット
- uspto-grants-2002_06
- 特許番号
- US06403561B1
反応ノート
読み込み中…