化工社化工社 化学情報印刷レポート · 研究参考用
6,7,8,9-tetrahydro-5H-benzo(7)annulene-5-carboxylic acid → N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6,7,8,9-tetrahydro-5H-benzocycloheptene-5-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6,7,8,9-tetrahydro-5H-benzo(7)annulene-5-carboxylic acid | HCID 14822604 | — |
| 反応物 | N-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylaniline | HCID 21957909 | — |
| 生成物 | N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6,7,8,9-tetrahydro-5H-benzocycloheptene-5-carboxamide | HCID 17854196 | 57% |
反応手順
By the reaction and treatment in the same manner as in Example 12 using 6,7,8,9-tetrahydro-5H-benzocycloheptene-5-carboxylic acid (0.29 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.37 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6,7,8,9-tetrahydro-5H-benzocycloheptene-5-carboxamide (0.36 g) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08198454B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-40128212572a4fbe8a6381a6bddd6a03 |
| 出典メモ | uspto-grants-2012_06 |