Ethyl Acetate → HCID 54306572、化合物

HRID 2186499ノート

反応式

HRID 2186499 の反応式
[N:1]([CH2:4][C@H:5]([O:12]C(=O)C)[CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=[N+]=[N-].[C:16](OCC)(=[O:18])[CH3:17]>[Pd]>[C:16]([NH:1][CH2:4][C@H:5]([OH:12])[CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:18])[CH3:17]

参加物

4

反応物 2

HCID 8857Ethyl AcetateHCID 53650499Ethyl (R)-4-Azido-3-Acetoxybutyrate

生成物 1

HCID 54306572HCID 54306572、化合物収率 81%

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

In a 200 ml autoclave were charged 4.50 g (20.9 mmol) of ethyl (R)-4-azido-3-acetoxybutyrate, 0.02 g of 5% Pd—C, and 5 ml of ethyl acetate, and the mixture was stirred at room temperature under a hydrogen pressure of 1000 KPa overnight. The catalyst was removed for concentration to give 3.20 g (81%) of the title compound.

後処理

  1. customThe catalyst was removed for concentration

出典と根拠

ORDレコード
ord-eae6768257f54157ae63cba32e021406
出典データセット
uspto-grants-2002_06
特許番号
US06403804B1

反応ノート

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