4-Hydroxybenzaldehyde → 4-(1-Methylbutyloxy)benzaldehyde
反応式
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[CH3:10][C@H:11](OS(C1C=CC(C)=CC=1)(=O)=O)[CH2:12][CH2:13][CH3:14].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:10][CH:11]([O:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1)[CH2:12][CH2:13][CH3:14]参加物
5
実験手順
40 g of 4-hydroxybenzaldehyde, 80 g of (S)-1-methylbutyl-p-toluene sulfonate and 46 g of potassium carbonate were refluxed in acetone for 12 hours, insoluble matters were removed from the reaction solution while the reaction solution was hot, and the solvent used was distilled out. The residue was purified by column chromatography to obtain 4-(1-methylbutyloxy)benzaldehyde (30).
後処理
- custominsoluble matters were removed from the reaction solution while the reaction solution
- distillationthe solvent used was distilled out
- customThe residue was purified by column chromatography
出典と根拠
- ORDレコード
- ord-e52079b7836c4de8a15af087dbeaa475
- 出典データセット
- uspto-grants-1995_06
- 特許番号
- US05425897
反応ノート
読み込み中…