Ethanol → 2,2'-Diamino-4,4'-dibromobiphenyl

HRID 219058

反応式

HRID 219058 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][C:9]=2[N+:15]([O-])=O)=[C:4]([N+:18]([O-])=O)[CH:3]=1.CCO.[OH-].[Na+]>Cl>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][C:9]=2[NH2:15])=[C:4]([NH2:18])[CH:3]=1

参加物

5

反応物 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 100466484,4'-Dibromo-2,2'-dinitro-1,1'-biphenyl

生成物 1

HCID 112215382,2'-Diamino-4,4'-dibromobiphenyl収率 67.5%

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

4,4′-dibromo-2,2′-dinitrobiphenyl (6.1 g, 15.17 mmol) was stirred in HCl 30 ml/EtOH 75 ml, Sn powder (7.2 g, 60.68 mmol) was added thereto, and then the reaction mixture was refluxed for 24 hours. Next, the reaction mixture was cooled to room temperature, neutralized with 10% NaOH solution, and then recrystallized in ethanol to obtain 4,4′-dibromo-2,2′-diaminobiphenyl (3.5 g, 67%). MS [M+H] 341.

後処理

  1. additionwas added
  2. temperaturethe reaction mixture was refluxed for 24 hours
  3. customrecrystallized in ethanol

出典と根拠

ORDレコード
ord-a89cd0efccb94178802fdbdc758cbc25
出典データセット
uspto-grants-2012_06
特許番号
US08198801B2

関連ノート

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