N-methyl-2-pyrrolidone → N-[4-(1-{1-(4-Chlorophenyl)-2-[5-(2-methoxypyridin-3-yl)-1,3-dihydro-2H-isoindol-2-yl]-2-oxoethyl}butyl)benzoyl]-beta-alanine

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:12]([C:16]2[CH:21]=[CH:20][C:19]([C:22]([NH:24][CH2:25][CH2:26][C:27]([O:29]CC)=[O:28])=[O:23])=[CH:18][CH:17]=2)[CH2:13][CH2:14][CH3:15])[C:9](O)=[O:10])=[CH:4][CH:3]=1.CN(C(ON1N=N[C:42]2[CH:43]=[CH:44][CH:45]=[N:46][C:41]1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.Br[C:66]1[CH:67]=[C:68]2[C:72](=[CH:73][CH:74]=1)[CH2:71][NH:70][CH2:69]2.CN1[C:80](=[O:81])CCC1>CCOC(C)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([CH:12]([C:16]2[CH:17]=[CH:18][C:19]([C:22]([NH:24][CH2:25][CH2:26][C:27]([OH:29])=[O:28])=[O:23])=[CH:20][CH:21]=2)[CH2:13][CH2:14][CH3:15])[C:9]([N:70]2[CH2:71][C:72]3[C:68](=[CH:67][CH:66]=[C:74]([C:42]4[C:41]([O:81][CH3:80])=[N:46][CH:45]=[CH:44][CH:43]=4)[CH:73]=3)[CH2:69]2)=[O:10])=[CH:6][CH:7]=1