Methanol → Ethyl 2-(3-chloropyrazin-2-yl)hydrazinecarbonothioylcarbamate
反応式
Cl.[Cl:2][C:3]1[C:8]([NH:9][NH2:10])=[N:7][CH:6]=[CH:5][N:4]=1.[C:11]([N:16]=[C:17]=[S:18])(=[O:15])[O:12][CH2:13][CH3:14].CO>C(Cl)(Cl)Cl>[Cl:2][C:3]1[C:8]([NH:9][NH:10][C:17]([NH:16][C:11](=[O:15])[O:12][CH2:13][CH3:14])=[S:18])=[N:7][CH:6]=[CH:5][N:4]=1参加物
5
実験手順
A solution of 2-chloro-3-hydrazinylpyrazine hydrochloride (3.32 g, 18.34 mmol) in anhydrous chloroform was treated with O-ethyl carbonisothiocyanatidate (1.9 mL, 16.11 mmol) at room temperature. Anhydrous methanol (10 mL) was added to the reaction mixture which was then concentrated under reduced pressure to yield ethyl 2-(3-chloropyrazin-2-yl)hydrazinecarbonothioylcarbamate (5.37 g) as an orange solid.
後処理
- concentrationwas then concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-c6302ec31c514e56878bab038da5a833
- 出典データセット
- uspto-grants-2012_12
- 特許番号
- US08329705B2
反応ノート
読み込み中…