Iodoethane → 4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-ethyl-1H-pyridin-2-one

反応式

[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:23])[N:13]([C:16]3[CH:21]=[CH:20][NH:19][C:18](=[O:22])[CH:17]=3)[C:14]=2[CH3:15])[CH:5]=[CH:6][CH:7]=1.[CH2:24](I)[CH3:25]>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:23])[N:13]([C:16]3[CH:21]=[CH:20][N:19]([CH2:24][CH3:25])[C:18](=[O:22])[CH:17]=3)[C:14]=2[CH3:15])[CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 6340Iodoethane

HCID 498725784-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-one

生成物 1

HCID 498725794-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-ethyl-1H-pyridin-2-one

実験手順

The title compound, white crystalline solid, MS: m/e=352.2, 354.1 (M+H+), was prepared in accordance with the general method of example 3 from 4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-one and ethyl iodide.

出典と根拠

ORDレコード: ord-174331d60bb04f61a86caebf3e051d0c
出典データセット: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08334287B2

反応ノート

読み込み中…