Methyl iodide → 4-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1-methyl-1H-pyridin-2-one

反応式

[CH3:1][C:2]1[N:3]([C:17]2[CH:22]=[CH:21][NH:20][C:19](=[O:23])[CH:18]=2)[C:4]([CH3:16])=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1.[CH3:24]I>>[CH3:1][C:2]1[N:3]([C:17]2[CH:22]=[CH:21][N:20]([CH3:24])[C:19](=[O:23])[CH:18]=2)[C:4]([CH3:16])=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1

参加物

反応物 2

HCID 6328Methyl iodide

HCID 581111894-(2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one

生成物 1

HCID 498727644-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1-methyl-1H-pyridin-2-one

実験手順

The title compound, brown solid, MS: m/e=318.2 (M+H+), was prepared in accordance with the general method of example 3 from 4-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1H-pyridin-2-one and methyl iodide.

出典と根拠

ORDレコード: ord-bc16341ecbdb487bba1f2b848fae2926
出典データセット: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08334287B2

反応ノート

読み込み中…