Trifluoroacetic acid → HCID 66727110、化合物
反応式
C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][N:12]=[C:11]2[NH:15][CH:16]=[CH:17][C:10]=12)(C)(C)C.[F:19][C:20]([F:25])([F:24])[C:21]([OH:23])=[O:22]>C(Cl)Cl>[F:19][C:20]([F:25])([F:24])[C:21]([OH:23])=[O:22].[NH:15]1[C:11]2=[N:12][CH:13]=[CH:14][C:9]([CH2:8][NH2:7])=[C:10]2[CH:17]=[CH:16]1参加物
4
実験手順
To a solution of (1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-carbamic acid tert-butyl ester (200 mg, 0.809 mmol) in CH2Cl2 (6 mL) was added trifluoroacetic acid (1.58 mL, 20.6 mmol). After 14 hours, the reaction was concentrated in vacuo to afford the title compound which was used in the without purification.
後処理
- concentrationthe reaction was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-169e5721d5da485fb0c28bc2c4986983
- 出典データセット
- uspto-grants-2012_12
- 特許番号
- US08338610B2
反応ノート
読み込み中…