関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phosphorus oxychloride | HCID 24813 | — |
| 反応物 | Sulfolane | HCID 31347 | — |
| 反応物 | 5-Acetamido-1-(acetyloxy)naphthalene-2-sulfonic acid | HCID 155698 | — |
| 生成物 | 2-Naphthalenesulfonyl chloride, 5-(acetylamino)-1-(acetyloxy)- | HCID 94125 | 81% |
反応手順
100 g of 1-acetoxy-5-acetaminonaphthalene-2-sulfonic acid was added to 500 ml of sulfolane, and 200 ml of phosphorus oxychloride was dropwise added thereto at 40° C. while stirring. After continuing stirring for about 1 hour, the reaction mixture was poured into 2 liters of ice-water, and the precipitated crystals were collected by filtration, washed with water until the filtrate did not show acidity, and air-dried as such for 24 hours to obtain 70 g (81% yield) of product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04358532 |
|---|
| 出典データセット | uspto-grants-1982_11 |
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| ORD ID | ord-b241a5edfd5e451ebbba5e3298b4e286 |
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| 出典メモ | uspto-grants-1982_11 |
|---|
