反应详情

温度

40 °C

100 g of 1-acetoxy-5-acetaminonaphthalene-2-sulfonic acid was added to 500 ml of sulfolane, and 200 ml of phosphorus oxychloride was dropwise added thereto at 40° C. while stirring. After continuing stirring for about 1 hour, the reaction mixture was poured into 2 liters of ice-water, and the precipitated crystals were collected by filtration, washed with water until the filtrate did not show acidity, and air-dried as such for 24 hours to obtain 70 g (81% yield) of product.

1. additionwas dropwise added
2. stirringAfter continuing stirring for about 1 hour
3. filtrationthe precipitated crystals were collected by filtration
4. washwashed with water until the filtrate
5. customair-dried as such for 24 hours