化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 5-(Chloromethyl)-2-methylpyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | (2-Methylpyrimidin-5-yl)methanol | HCID 14686706 | — |
| 生成物 | 5-(Chloromethyl)-2-methylpyrimidine | HCID 14686699 | — |
反応手順
A solution of (2-methylpyrimidin-5-yl)methanol (95 mg, 0.77 mmol) in thionyl chloride (1 mL) was stirred at room temperature for 1 h. The mixture was concentrated to dryness and used without purification. LCMS MH+ 143.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09359359B2 |
| 出典データセット | uspto-grants-2016_06 |
| ORD ID | ord-2a2b5487c26648388f8b0c144ea6dbcf |
| 出典メモ | uspto-grants-2016_06 |