2-(3-Methoxyphenyl)-4-methyl-1,3-oxazole → HCID 59679628、化合物
反応式
C[O:2][C:3]1[CH:4]=[C:5]([C:9]2[O:10][CH:11]=[C:12]([CH3:14])[N:13]=2)[CH:6]=[CH:7][CH:8]=1>Br>[CH3:14][C:12]1[N:13]=[C:9]([C:5]2[CH:4]=[C:3]([OH:2])[CH:8]=[CH:7][CH:6]=2)[O:10][CH:11]=1参加物
3
実験手順
A solution of 2-(3-methoxyphenyl)-4-methyloxazole (1.1 g, 5.79 mmol) in aqueous hydrogen bromide (10 mL, 48% w/w) was heated to 100° C. for 16 h. The mixture was concentrated to give 3-(4-methyloxazol-2-yl)phenol (0.97 g, crude), which was used without purification. LCMS MH+ 176.
後処理
- concentrationThe mixture was concentrated
出典と根拠
- ORDレコード
- ord-ba6771fb9bb042fd8a3a07edbacda34e
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09359359B2
反応ノート
読み込み中…